2-methyl-3-phenylpropanol

Base Information

  • Chemical Name: 2-methyl-3-phenylpropanol
  • CAS No.: 7384-80-7

Top Quality Chinese Factory supply 7384-80-7 2-methyl-3-phenylpropanol

  • Molecular Formula: C10H14O
  • Molecular Weight: 150.221
  • Vapor Pressure: 0.0147mmHg at 25°C 
  • Melting Point: 84 °C 
  • Boiling Point: 246.1°C at 760 mmHg 
  • PKA: 15.03±0.10(Predicted) 
  • Flash Point: 106.2°C 
  • PSA: 20.23000 
  • Density: 0.98g/cm3 
  • LogP: 1.85750 

2-methyl-3-phenylpropanol(Cas 7384-80-7) Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 57, p. 2522, 1979 DOI: 10.1139/v79-404

InChI:InChI=1/C10H14O/c1-9(8-11)7-10-5-3-2-4-6-10/h2-6,9,11H,7-8H2,1H3

7384-80-7 Relevant articles

Highly efficient NHC-iridium-catalyzed β-methylation of alcohols with methanol at low catalyst loadings

Lu, Zeye,Zheng, Qingshu,Zeng, Guangkuo,Kuang, Yunyan,Clark, James H.,Tu, Tao

, p. 1361 - 1366 (2021/06/30)

The methylation of alcohols is of great ...

Your mother was right, washing matters: An alkyne-analog of ibuprofen reveals unwanted reactivity of aromatic compounds with proteins during copper-catalyzed click chemistry

Cutolo, Giuliano,Pratt, Matthew R.,Shankar, Sahiti N.

supporting information, (2021/07/19)

Bioorthogonal chemistry, in particular t...

Deep eutectic solvents as H2-sources for Ru(II)-catalyzed transfer hydrogenation of carbonyl compounds under mild conditions

Cavallo, Marzia,Arnodo, Davide,Mannu, Alberto,Blangetti, Marco,Prandi, Cristina,Baratta, Walter,Baldino, Salvatore

supporting information, (2021/02/22)

The employment of easily affordable ruth...

A Water/Toluene Biphasic Medium Improves Yields and Deuterium Incorporation into Alcohols in the Transfer Hydrogenation of Aldehydes

Ruiz-Casta?eda, Margarita,Santos, Lucía,Manzano, Blanca R.,Espino, Gustavo,Jalón, Félix A.

, p. 1358 - 1372 (2021/03/16)

Deuterium labeling is an interesting pro...

7384-80-7 Process route

allylbenzene
300-57-2,57807-91-7

allylbenzene

carbon monoxide
201230-82-2

carbon monoxide

phenylpropane
103-65-1

phenylpropane

4-phenyl-butan-1-ol
3360-41-6

4-phenyl-butan-1-ol

2-phenylbutan-1-ol
2035-94-1,89104-46-1

2-phenylbutan-1-ol

2-methyl-3-phenylpropanol
22436-06-2,77943-96-5,78964-61-1,7384-80-7

2-methyl-3-phenylpropanol

Conditions
Conditions Yield
With dodecacarbonyl-triangulo-triruthenium; 2-(dicyclohexylphosphino)-1-methyl-1H-imidazole; water; hydrogen; lithium chloride; In 1-methyl-pyrrolidin-2-one; at 130 ℃; for 20h; under 60 Torr; regioselective reaction; Autoclave;
57%
7%
25%
9 %Chromat.
1-propenylbenzene
873-66-5

1-propenylbenzene

carbon monoxide
201230-82-2

carbon monoxide

4-phenyl-butan-1-ol
3360-41-6

4-phenyl-butan-1-ol

2-phenylbutan-1-ol
2035-94-1,89104-46-1

2-phenylbutan-1-ol

2-methyl-3-phenylpropanol
22436-06-2,77943-96-5,78964-61-1,7384-80-7

2-methyl-3-phenylpropanol

Conditions
Conditions Yield
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); 2-(dicyclohexylphosphanyl)-1-(2-methoxyphenyl)-1H-imidazole; hydrogen; In toluene; at 160 ℃; for 24h; under 37503.8 Torr; Overall yield = 88 %Chromat.; regioselective reaction; Autoclave; Inert atmosphere;
39%
19%

7384-80-7 Upstream products

  • 5445-77-2
    5445-77-2

    (2S)-2-methyl-3-phenylpropanal

  • 1009-67-2
    1009-67-2

    2-methyl-3-phenylpropionic acid

  • 100-39-0
    100-39-0

    benzyl bromide

  • 155956-27-7
    155956-27-7

    (2'R,3'R,5R)-(-)-1-(3'-hydroxy-2'-methyl-3'-phenyl-1'-oxopropyl)-3,3,5-trimethyl-2-pyrrolidinone

7384-80-7 Downstream products

  • 111539-83-4
    111539-83-4

    Toluene-4-sulfonic acid (S)-2-methyl-3-phenyl-propyl ester

  • 5445-77-2
    5445-77-2

    (2S)-2-methyl-3-phenylpropanal

  • 67180-08-9
    67180-08-9

    (2S,3S)-threo-3-Methyl-4-phenyl-2-butanol

  • 2550-27-8
    2550-27-8

    (3S)-3-methyl-4-phenylbutan-2-one

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