PROCHLORPERAZINE MALEATE

Base Information

  • Chemical Name: PROCHLORPERAZINE MALEATE
  • CAS No.: 84-02-6

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What is the PROCHLORPERAZINE MALEATE ?

PROCHLORPERAZINE MALEATE is Off-White Powder, while it's Molecular Formula is C20H24ClN3S•2C4H4O4. Used in Pharmaceutical Industry:
Prochlorperazine maleate is used as an antipsychotic agent for its high potency and effectiveness in treating various mental health conditions.
Used in Oncology:
Prochlorperazine maleate is used to increase tumor cell antigen presentation, enhancing the efficacy of anti-tumor monoclonal antibodies (mAbs) in cancer treatment.
Used in Migraine Treatment:
Prochlorperazine maleate is used as an antimigraine agent, helping to alleviate the symptoms and frequency of migraine headaches.
Used in Antiemetic Therapy:
Prochlorperazine maleate is used as an antiemetic agent, primarily due to its high potency and effectiveness in preventing and treating nausea and vomiting.

What is the CAS number for PROCHLORPERAZINE MALEATE ?

The CAS number of PROCHLORPERAZINE MALEATE is 84-02-6.

More information of PROCHLORPERAZINE MALEATE 84-02-6 are:

Synonyms

PROCHLORPERAZINE DIMALEATE;PROCHLORPERAZINE DIMALEATE SALT;PROCHLORPERAZINE MALEATE;2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine,dimaleate;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10h-phenothiazin(z)-2-but;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinedimaleate;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1:2);buccastem

CAS?Number

84-02-6

Molecular Formula

C20H24ClN3S•2C4H4O4

Molecular Weight

606.096

Melting Point

228ºC

Boiling Point

524.8 °C at 760 mmHg

Flash Point

271.2 °C

HS CODE

2934302300

PSA

184.22000

LogP

3.94460

Pka

pKa 8.1(H2O,t =24±1) (Uncertain)

What is PROCHLORPERAZINE MALEATE (84-02-6) used for?

Prochlorperazine maleate (84-02-6) inhibits dynamin and clathrin-mediated endocytosis (CME) with an IC50=5.8 μM for CME.1?Increases tumor cell antigen presentation enhancing the efficacy of anti-tumor mAbs.2?A clinically useful antipsychotic agent3?with antimigraine4?and antiemetic activity5.

InChI:InChI=1/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)

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