Methyl (triphenylphosphoranylidene)acetate
Base Information
- Chemical Name: Methyl (triphenylphosphoranylidene)acetate
- CAS No.: 2605-67-6
Cost-effective and customizable Methyl (triphenylphosphoranylidene)acetate 2605-67-6 supplier
- Molecular Formula: C21H19O2P
- Molecular Weight: 334.354
- Appearance/Colour: white to off-white powder
- Vapor Pressure: 0mmHg at 25°C
- Melting Point: 168-172 °C(lit.)
- Refractive Index: 1.608
- Boiling Point: 479.138 °C at 760 mmHg
- Flash Point: 256.768 °C
- PSA： 36.11000
- Density: 1.177 g/cm3
- LogP: 2.95570
Methyl (triphenylphosphoranylidene)acetate(Cas 2605-67-6) Usage
|
Purification Methods |
Crystallise it by dissolving in it AcOH and adding pet ether (b 40-50o) to give colourless plates. UV max (A 1mm ): 222nm (865) and 268nm (116) [Isler et al. Helv Chim Acta 40 1242 1957]. [Beilstein 16 IV 977.] |
InChI:InChI=1/C21H19O2P/c1-23-21(22)17-24(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20/h2-17H,1H3
2605-67-6 Relevant articles
Organocatalyzed [2+2] Cycloaddition Reactions between Quinone Imine Ketals and Allenoates
Liu, Teng,He, Chixian,Wang, Fan,Shen, Xiang,Li, Yongqin,Lang, Man,Li, Guijun,Huang, Chao,Cheng, Feixiang
, p. 518 - 526 (2020/10/12)
A new cycloaddition reaction of quinone ...
Catalytic asymmetric [3+2] cycloaddition of isomünchnones with methyleneindolinones
Feng, Xiaoming,Hu, Xinyue,Lin, Lili,Wang, Kaixuan,Xu, Chaoran,Zhou, Yuqiao
, p. 8917 - 8920 (2021/09/10)
An efficient enantioselective [3+2] cycl...
Enantioselective Rauhut–Currier Reaction with β-Substituted Acrylamides Catalyzed by N-Heterocyclic Carbenes
Pitchumani, Venkatachalam,Breugst, Martin,Lupton, David W.
supporting information, p. 9413 - 9418 (2021/12/09)
β-Substituted acrylamides have low elect...
Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters
Frydrych, Ivo,Urban, Milan,?arek, Jan,Benická, Sandra,D?ubák, Petr,Gurská, Soňa,Hajdúch, Marián,Kotulová, Jana,Li?ková, Barbora,Olejníková, Denisa,Pokorny, Jan
, (2021/07/28)
A set of new substituted dienes were syn...
2605-67-6 Process route
-
-
1779-58-4
(methyloxycarbonylmethyl)triphenylphosphonium bromide
-
-
21204-67-1,2605-67-6
methyl (triphenylphosphoranylidene)acetate
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
water;
|
100%
|
|
With
sodium hydroxide;
In
dichloromethane; water;
|
100%
|
|
With
sodium hydroxide; water;
In
dichloromethane;
|
99%
|
|
With
sodium hydroxide;
In
dichloromethane; water;
Inert atmosphere;
|
96%
|
|
With
sodium carbonate;
In
dichloromethane;
for 0.333333h;
|
95%
|
|
With
sodium hydroxide;
In
water;
|
93%
|
|
With
sodium hydroxide;
In
dichloromethane; water;
at 20 ℃;
for 2h;
|
90%
|
|
With
sodium hydroxide;
In
water;
at 0 ℃;
for 0.333333h;
Inert atmosphere;
|
89%
|
|
With
sodium hydroxide;
In
dichloromethane; water;
|
88%
|
|
With
sodium hydroxide;
|
|
|
With
sodium amide;
In
toluene;
|
|
|
|
|
|
With
triethylamine;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
|
|
|
With
sodium amide;
In
benzene;
at 20 ℃;
for 24h;
|
|
|
With
sodium hydroxide; tetrabutylammomium bromide;
In
methanol; dichloromethane; water;
at 0 - 20 ℃;
for 1h;
|
|
|
With
sodium hydroxide;
In
water;
for 1h;
|
57.4 g
|
|
With
sodium hydroxide;
In
water;
|
|
|
With
sodium methylate;
|
|
|
With
sodium hydroxide;
In
dichloromethane; water;
for 0.5h;
|
70 g
|
|
With
sodium hydroxide;
In
dichloromethane;
Inert atmosphere;
|
22.1 g
|
|
With
triethylamine;
In
water;
for 1h;
|
|
|
With
water; sodium hydroxide;
for 0.5h;
|
|
|
With
sodium hydroxide;
In
dichloromethane; water;
|
|
|
With
sodium hydroxide;
In
water;
|
|
|
With
sodium hydroxide;
In
dichloromethane; water;
Inert atmosphere;
Schlenk technique;
|
22.1 g
|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 - 20 ℃;
for 0.5h;
|
2.26 g
|
|
With
sodium hydroxide;
In
dichloromethane; water;
at 20 ℃;
for 0.333333h;
|
|
|
With
potassium tert-butylate;
In
tetrahydrofuran;
at 20 ℃;
Inert atmosphere;
|
|
|
With
sodium carbonate;
In
dichloromethane; water;
at 0 - 20 ℃;
for 0.5h;
|
|
|
With
sodium carbonate;
In
dichloromethane; water;
at 20 ℃;
for 0.25h;
|
|
|
With
potassium carbonate;
In
dichloromethane;
at 20 ℃;
for 0.5h;
|
|
|
With
water; sodium hydroxide;
In
dichloromethane;
at 20 ℃;
for 2h;
|
|
|
(methyloxycarbonylmethyl)triphenylphosphonium bromide;
With
potassium tert-butylate;
for 0.5h;
Schlenk technique;
In
tetrahydrofuran;
for 1h;
Schlenk technique;
|
-
-
96-32-2
bromoacetic acid methyl ester
-
-
603-35-0
triphenylphosphine
-
-
21204-67-1,2605-67-6
methyl (triphenylphosphoranylidene)acetate
| Conditions | Yield |
|---|---|
|
bromoacetic acid methyl ester; triphenylphosphine;
In
ethyl acetate;
With
sodium hydroxide;
In
water;
for 0.333333h;
|
96%
|
|
In
ethyl acetate;
at 20 ℃;
|
93%
|
|
In
toluene;
|
93%
|
|
bromoacetic acid methyl ester; triphenylphosphine;
In
ethyl acetate;
at 20 ℃;
With
sodium hydroxide;
In
water; benzene;
at 20 ℃;
for 1h;
|
84%
|
|
In
benzene;
for 2.16667h;
|
83%
|
|
bromoacetic acid methyl ester; triphenylphosphine;
In
benzene;
for 1h;
With
triethylamine;
In
water; benzene;
for 1h;
|
|
|
bromoacetic acid methyl ester; triphenylphosphine;
In
toluene;
at 80 ℃;
for 12h;
With
potassium hydroxide;
In
dichloromethane; water;
|
|
|
bromoacetic acid methyl ester; triphenylphosphine;
In
toluene;
at 20 ℃;
for 24h;
With
sodium base;
In
dichloromethane; water;
|
|
|
bromoacetic acid methyl ester; triphenylphosphine;
In
ethyl acetate;
at 20 ℃;
With
sodium hydroxide;
In
dichloromethane; water;
at 20 ℃;
for 1h;
|
2605-67-6 Upstream products
-
1779-58-4
(methyloxycarbonylmethyl)triphenylphosphonium bromide
-
2181-97-7
(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
-
603-35-0
triphenylphosphine
-
96-32-2
bromoacetic acid methyl ester
2605-67-6 Downstream products
-
4895-61-8
Triphenylphosphin-cinnamoyl-methoxycarbonyl-methylen
-
96277-01-9
methyl 3-(2-chlorophenyl)-3-oxo-2-(triphenylphosphoranylidene)propanoate
-
95156-66-4
α-Cinnamyl-zimtsaeure
-
96372-85-9
methyl 3-oxo-3-(p-tolyl)-2-(triphenylphosphoranylidene)propanoate